Update Multiple app variables at the same time

Im using an rest api (via create record), but my output have 32 relevant variables from the return.

Is there any easy way or i need to create different flows for update the app.variables ?

I tried to manipulate them with custom javascript but i didnt find a way to update the app variables from custom javascript tag.

Why not use list or obj in your app variable? You only have to deal with one variable and one flow function